| Name |
p38 MAPK (Thr180/Tyr182) Antibody
|
| Supplier |
ABBIOTEC
|
| Catalog |
252567
|
| Prices |
$405.00
|
| Sizes |
100 µl
|
| Host |
Rabbit
|
| Clonality |
Polyclonal
|
| Isotype |
Rabbit Ig
|
| Applications |
ELISA IHC WB
|
| Species Reactivities |
Bovine
|
| Antigen |
KLH-conjugated synthetic phosphopeptide encompassing a sequence surrounding Thr180/Tyr182 of rat p38 MAPK.
|
| Purity/Format |
Each vial contains 0.1 ml IgG in HEPES pH7.5, 150 mM NaCl, 0.01% BSA and 50% glycerol. Antibody was purified by immunogen affinity chromatography on phosphopeptide and nonphosphopeptide.
|
| Description |
Mitogen-activated protein kinase p38 alpha (p38 MAPK) responds to activation by environmental stress, pro-inflammatory cytokines and lipopolysaccharide (LPS) by phosphorylating a number of transcription factors, such as ELK1 and ATF2 and several downstream kinases, such as MAPKAPK2 and MAPKAPK5. P38 MAPK plays a critical role in the production of some cytokines, for example IL-6. P38 MAPK plays a role in stabilization of EPO mRNA during hypoxic stress. p38 MAPK is activated by a dual specificity kinase that phosphorylates Thr180 and Tyr182.
|
| Gene |
Mapk14
|
| Supplier Page |
Shop
|
The p38 MAPK (Thr180/Tyr182) Antibody is used in Western blot to detect p38 MAPK phosphorylated at Thr180/Tyr182 in HeLa cell lysates untreated (left lane) or UV-irradiated (right lane).