Anti-Aggrecan ARGxx antibody [BC-3]

• Supplier: Abcam
• Catalog: ab3773
• Prices: $379.00
• Sizes: 1 ml
• Host: Mouse
• Clonality: Monoclonal
• Isotype: IgG1
• Clone: BC-3
• Applications: ELISA IHC-P IHC-F WB ELISA
• Species Reactivities: Rat, Sheep, Rabbit, Horse, Guinea Pig, Bovine, Cat, Dog, Human, Pig
• Antigen: ARGSV
• Description: Mouse Monoclonal
• Gene: ACAN
• Conjugate: Unconjugated

Product References

PKCepsilon signalling activates ERK1/2, and regulates aggrecan, ADAMTS5, and - PKCepsilon signalling activates ERK1/2, and regulates aggrecan, ADAMTS5, and

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TNF-alpha and IL-1beta promote a disintegrin-like and metalloprotease with - TNF-alpha and IL-1beta promote a disintegrin-like and metalloprotease with

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Mechanical load inhibits IL-1 induced matrix degradation in articular cartilage. - Mechanical load inhibits IL-1 induced matrix degradation in articular cartilage.

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MAPKs are essential upstream signaling pathways in proteolytic cartilage - MAPKs are essential upstream signaling pathways in proteolytic cartilage

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Aggrecanase- and matrix metalloproteinase-mediated aggrecan degradation is - Aggrecanase- and matrix metalloproteinase-mediated aggrecan degradation is

Madsen SH, Sumer EU, Bay-Jensen AC, Sondergaard BC, Qvist P, Karsdal MA. Biomarkers. 2010 May;15(3):266-76.

Patients with rheumatoid arthritis have an altered circulatory aggrecan profile. - Patients with rheumatoid arthritis have an altered circulatory aggrecan profile.

Rousseau JC, Sumer EU, Hein G, Sondergaard BC, Madsen SH, Pedersen C, Neumann T, Mueller A, Qvist P, Delmas P, Karsdal MA. BMC Musculoskelet Disord. 2008 May 28;9:74.

Cartilage degradation is fully reversible in the presence of aggrecanase but not - Cartilage degradation is fully reversible in the presence of aggrecanase but not

Karsdal MA, Madsen SH, Christiansen C, Henriksen K, Fosang AJ, Sondergaard BC. Arthritis Res Ther. 2008;10(3):R63.

Induction of increased cAMP levels in articular chondrocytes blocks matrix - Induction of increased cAMP levels in articular chondrocytes blocks matrix

Karsdal MA, Sumer EU, Wulf H, Madsen SH, Christiansen C, Fosang AJ, Sondergaard BC. Arthritis Rheum. 2007 May;56(5):1549-58.

Developing an alginate/chitosan hybrid fiber scaffold for annulus fibrosus cells. - Developing an alginate/chitosan hybrid fiber scaffold for annulus fibrosus cells.

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