Anti-ATM antibody [Y170]

• Supplier: Abcam
• Catalog: ab32420
• Prices: $403.00
• Sizes: 100 µl
• Host: Rabbit
• Clonality: Monoclonal
• Isotype: IgG
• Clone: Y170
• Applications: WB ICC/IF ICC/IF
• Species Reactivities: Human
• Antigen: Synthetic peptide (the amino acid sequence is considered to be commercially sensitive) corresponding to Human ATM
• Blocking Peptide: ATM peptide
• Description: Rabbit Monoclonal
• Gene: ATM
• Conjugate: Unconjugated

Product images

Immunofluorescent staining of HeLa cells (fixed with 4% PFA) with purified ab32420 at a dilution of 1/250. An Alexa Fluor® 555 goat anti-rabbit antibody was used as the secondary at a dilution of 1/200. The panel on the right shows the DAPI counter-staining.

All lanes : Anti-ATM antibody [Y170] (ab32420) at 1/3000 dilution (Purified)Lane 1 : HeLa cell lysateLane 2 : HEK293 cell lysateLysates/proteins at 10 µg per lane.SecondaryHRP goat anti-rabbit (H+L) at 1/1000 dilution

Immunofluorescent staining of  293 cells with ab32420 at a 1/100 dilution.

Anti-ATM antibody [Y170] (ab32420) at 1/5000 dilution (Unpurified) + 293 cell lysate.

Product References

Having pancreatic cancer with tumoral loss of ATM and normal TP53 protein - Having pancreatic cancer with tumoral loss of ATM and normal TP53 protein

Kim H, Saka B, Knight S, Borges M, Childs E, Klein A, Wolfgang C, Herman J, Adsay VN, Hruban RH, Goggins M. Clin Cancer Res. 2014 Apr 1;20(7):1865-72.

Functional and molecular defects of hiPSC-derived neurons from patients with ATM - Functional and molecular defects of hiPSC-derived neurons from patients with ATM

Carlessi L, Fusar Poli E, Bechi G, Mantegazza M, Pascucci B, Narciso L, Dogliotti E, Sala C, Verpelli C, Lecis D, Delia D. Cell Death Dis. 2014 Jul 17;5:e1342.

WISP-1 contributes to fractionated irradiation-induced radioresistance in - WISP-1 contributes to fractionated irradiation-induced radioresistance in

Li WF, Zhang L, Li HY, Zheng SS, Zhao L. PLoS One. 2014 Apr 11;9(4):e94751.

Mutation at intronic repeats of the ataxia-telangiectasia mutated (ATM) gene and - Mutation at intronic repeats of the ataxia-telangiectasia mutated (ATM) gene and

Kim HS, Choi SI, Min HL, Kim MA, Kim WH. PLoS One. 2013 Dec 6;8(12):e82769.

Resistance to DNA-damaging treatment in non-small cell lung cancer - Resistance to DNA-damaging treatment in non-small cell lung cancer

Lundholm L, Haag P, Zong D, Juntti T, Mork B, Lewensohn R, Viktorsson K. Cell Death Dis. 2013 Jan 31;4:e478.

Loss of BRCA1 expression leads to worse survival in patients with gastric - Loss of BRCA1 expression leads to worse survival in patients with gastric

Zhang ZZ, Liu YJ, Yin XL, Zhan P, Gu Y, Ni XZ. World J Gastroenterol. 2013 Mar 28;19(12):1968-74.

The kinase activity of ataxia-telangiectasia mutated interferes with adenovirus - The kinase activity of ataxia-telangiectasia mutated interferes with adenovirus

Gautam D, Bridge E. J Virol. 2013 Aug;87(15):8687-96.

Regulation of nucleotide excision repair by nuclear lamin b1. - Regulation of nucleotide excision repair by nuclear lamin b1.

Butin-Israeli V, Adam SA, Goldman RD. PLoS One. 2013 Jul 24;8(7):e69169.

ATM is required for the repair of Topotecan-induced replication-associated - ATM is required for the repair of Topotecan-induced replication-associated

Kocher S, Spies-Naumann A, Kriegs M, Dahm-Daphi J, Dornreiter I. Radiother Oncol. 2013 Sep;108(3):409-14.

The complexity of DNA double strand breaks is a critical factor enhancing - The complexity of DNA double strand breaks is a critical factor enhancing

Yajima H, Fujisawa H, Nakajima NI, Hirakawa H, Jeggo PA, Okayasu R, Fujimori A. DNA Repair (Amst). 2013 Nov;12(11):936-46.