4E Binding Protein 1 Antibody Kit (Protein Synthesis Initiation Factor 4E Binding Protein,eIF-4EBP1, PHAS-1, PHAS-I, Eukaryotic Translation Initiation Factor BP)

• Supplier: USBiological Life Science
• Catalog: 0004-18C
• Applications: ELISA WB IP IHC ICC/IF FC
• Description: PHAS-I, also known as eIF4E-BP1 and PHAS-II,-III (eIF4E-BP2, 3), are members of a family of proteins that regulate eukaryotic translation initiation which is mediated by the cap structure (m7GpppN, where N=any nucleotide) present at the 5í end of all cellular mRNAs, except organellar (1). The m7 cap is essential for the translation of most mRNA because it directs the translation machinery of the 5í end of the mRNA via its interaction with the cap binding protein, the translation initiation factor 4E(eIF4E) (2).