| Name |
Decitabine, Free Base
|
| Supplier |
Biorbyt
|
| Catalog |
orb153611
|
| Prices |
$323.00, $408.00, $408.00, $451.00, $604.00, $927.00, $1,411.00, $2,023.00
|
| Sizes |
50 mg, 100 mg, 200 mg, 250 mg, 500 mg, 1 g, 2 g, 5 g
|
| Cas Number |
[2353-33-5]
|
| Pubchem |
451668
|
| Chemical Name |
4-amino-1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,3,5-triazin-2-one
|
| Formula |
C8H12N4O4
|
| Molecular Weight |
228.21 g/mol
|
| Purity |
>99% pure
|
| Description |
Decitabine is a cytosine nucleoside analog and inhibits further DNA methylation after incorporated into DNA. Decitabine has shown activity in some hematologic disorders including myelodysplastic syndromes (MDS), acute myelogenous leukemia (AML) and chronic myelogenous leukemia (CML). Treatment of patients with sickle cell disease (SSD) with subcutaneous decitabine increased fetal hemoglobin (HbF) levels and improved SSD pathophysiology such as red cell adhesion, endothelial damage, and coagulation pathway activity without cytotoxicity.
|
| Supplier Page |
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