JNK Inhibitor XIV, SR-3306 - Calbiochem
| Name | JNK Inhibitor XIV, SR-3306 - Calbiochem |
|---|---|
| Supplier | EMD Millipore |
| Catalog | 420147 |
| Formula | C₂₈H₂₆N₈O |
| Purity | ≥95% by HPLC |
| Description | A cell-permeable, blood-brain-barrier-permeant, and orally available anilinopyrimidine compound that acts as a highly selective, potent, reversible, and ATP-competitive JNK inhibitor (IC 50 = 67, 283, and 159 nM against JNK1, JNK2, and JNK3, respectively), exhibiting little or no activity toward a panel of more than 300 kinases, including p38 (IC 50 >20 µM) |
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