IRE1 Inhibitor II - Calbiochem

• Supplier: EMD Millipore
• Catalog: 412511
• Formula: C₁₅H₁₃NO₄
• Purity: ≥97% by HPLC
• Description: A cell-permeable salicylaldehyde compound that is shown to inhibit ER stress-induced Xbp1 mRNA splicing (100% inhibition by ≤25 µM in Tunicamycin-treated U373 cultures) in a reversible manner, presumably due to IRE1 inhibition via the same molecular/chemical mechanism as 4µ8C (Cat. No. 412512 ) and STF083010 (Cat. No. 412510 )

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