CRAC Channel Inhibitor IV, EVP4593 - Calbiochem
| Name | CRAC Channel Inhibitor IV, EVP4593 - Calbiochem |
|---|---|
| Supplier | EMD Millipore |
| Catalog | 481417 |
| Formula | C₂₂H₂₀N₄O |
| Purity | ≥98% by HPLC |
| Description | A cell-permeable quinazoline derivative that blocks PMA/PHA-induced NF-κB activation in Jurkat cells (IC 50 = 11 nM), but has no effect on PKC kinase, and exhibits an anti-inflammatory effect on carrageenin-induced paw edema in rats (1 mg/kg, i.p.) |
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