Fatostatin - CAS 298197-04-3 - Calbiochem
| Name | Fatostatin - CAS 298197-04-3 - Calbiochem |
|---|---|
| Supplier | EMD Millipore |
| Catalog | 341329 |
| Cas Number | 298197-04-3 |
| Formula | C₁₈H₁₈N₂S•HBr |
| Purity | ≥95% by HPLC |
| Description | A cell-permeable diarylthiazole compound that prevents the cellular activation of the SREBP-1/2 (Sterol Regulatory Element Binding Proteins 1/2) precursors to the active nuclear forms (>95% inhibition at 20 µM in CHO-K1 cells) by blocking SREBPs-SCAP (SREBP Cleavage-Activating Protein) ER to Golgi translocation with little effect against the transcription activity of the mature SREBPs |
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