Name | PDGFR Tyrosine Kinase Inhibitor VI, SU6668 - CAS 210644-62-5 - Calbiochem |
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Supplier | EMD Millipore |
Catalog | 521235 |
Cas Number | 210644-62-5 |
Formula | C₁₈H₁₈N₂O₃ |
Purity | ≥97% by HPLC |
Description | A cell-permeable indolinone compound that acts as a potent ATP-competitive inhibitor against RTKs (receptor tyrosine kinases) Kit, PDGFRβ, VEGFR2 (Flk-1/KDR), FGFR1 activity in vitro (IC 50 = 0.01, 0.1, 3.9, and 3.8 µM, respectively) and PDGF/VEGF/bFGF-mediated angiogenesis and tumor development in vivo |
Supplier Page | Shop |