Oligomycin
| Name | Oligomycin |
|---|---|
| Supplier | Cell Signaling Technology |
| Catalog | 9996 |
| Prices | $99.00 |
| Sizes | 5 mg |
| Formula | IsomerA:C45H74O11 |
| Molecular Weight | (Average based on isomer content) |
| Purity | 97% |
| Description | During oxidative phosphorylation in mitochondria, the electron transport system pumps H + from the matrix into the intermembrane compartment. This process generates a H + gradient across the mitochondrial inner membrane. This H + gradient is used to drive mitochondrial F o F 1 ATPase to convert ADP to ATP. Oligomycin, an antibiotic from Streptomyces diastatochromogenes , blocks oxidative phosphorylation by binding to the F o part of the ATPase to inhibit its activity (1-3). |
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