( R )-PFI 2 hydrochloride

• Supplier: R&D Systems
• Catalog: 4892
• Prices: $299.00
• Sizes: 10 mg
• Cas Number: 1627607-87-7
• Chemical Name: (1R)-1-[[3-(Trifluoromethyl)phenyl]methyl]-2-oxo-2-(1-pyrrolidinyl)ethyl]1,2,3,4-tetrahydro-6-isoquinolinesulfonamidehydrochloride
• Formula: C23H25F4N3O3S.HCl
• Molecular Weight: 535.98
• Purity: >97%

Product References

Repression of hypoxia-inducible factor alpha signaling by Set7-mediated - Repression of hypoxia-inducible factor alpha signaling by Set7-mediated

Liu X, Chen Z, Xu C, Leng X, Cao H, Ouyang G, Xiao W. Nucleic Acids Res. 2015 May 26;43(10):5081-98.

(R)-PFI-2 is a potent and selective inhibitor of SETD7 methyltransferase activity - (R)-PFI-2 is a potent and selective inhibitor of SETD7 methyltransferase activity

Barsyte-Lovejoy D, Li F, Oudhoff MJ, Tatlock JH, Dong A, Zeng H, Wu H, Freeman SA, Schapira M, Senisterra GA, Kuznetsova E, Marcellus R, Allali-Hassani A, Kennedy S, Lambert JP, Couzens AL, Aman A, Gingras AC, Al-Awar R, Fish PV, Gerstenberger BS, Roberts L, Benn CL, Grimley RL, Braam MJ, Rossi FM, Sudol M, Brown PJ, Bunnage ME, Owen DR, Zaph C, Vedadi M, Arrowsmith CH. Proc Natl Acad Sci U S A. 2014 Sep 2;111(35):12853-8. doi: