6-Thioguanine

• Supplier: R&D Systems
• Catalog: 4061
• Prices: $45.00
• Sizes: 50 mg
• Cas Number: 154-42-7
• Chemical Name: 2-Amino-6-mercaptopurine
• Formula: C5H5N5S
• Molecular Weight: 167.19
• Purity: >99%

Product References

6-Thioguanine perturbs cytosine methylation at the CpG dinucleotide site by DNA - 6-Thioguanine perturbs cytosine methylation at the CpG dinucleotide site by DNA

Wang H, Wang Y. Biochemistry. 2009 Mar 17;48(10):2290-9.

6-thioguanine selectively kills BRCA2-defective tumors and overcomes PARP - 6-thioguanine selectively kills BRCA2-defective tumors and overcomes PARP

Issaeva N, Thomas HD, Djureinovic T, Jaspers JE, Stoimenov I, Kyle S, Pedley N, Gottipati P, Zur R, Sleeth K, Chatzakos V, Mulligan EA, Lundin C, Gubanova E, Kersbergen A, Harris AL, Sharma RA, Rottenberg S, Curtin NJ, Helleday T. Cancer Res. 2010 Aug 1;70(15):6268-76.

6-Thioguanine reactivates epigenetically silenced genes in acute lymphoblastic - 6-Thioguanine reactivates epigenetically silenced genes in acute lymphoblastic

Yuan B, Zhang J, Wang H, Xiong L, Cai Q, Wang T, Jacobsen S, Pradhan S, Wang Y. Cancer Res. 2011 Mar 1;71(5):1904-11.