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AEG 40730 dihydrochloride

Name AEG 40730 dihydrochloride
Supplier R&D Systems
Catalog 5330
Prices $265.00, $1,085.00
Sizes 10 mg, 50 mg
Chemical Name 222,Trifluoro-N-[[(2S)-1-(N-methyl-L-analyl-L-threonyl)-2-pyrrolidinyl]methyl]-N-(2-phenylethyl)acetamide,diethyletherwith2,4-hexadiyne-1.6-dioldihydrochloride
Formula C52H68F6N8O8.2HCl
Molecular Weight 1120.06
Purity >98%
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Product References

cIAP1 and cIAP2 facilitate cancer cell survival by functioning as E3 ligases that - cIAP1 and cIAP2 facilitate cancer cell survival by functioning as E3 ligases that

Bertrand MJ, Milutinovic S, Dickson KM, Ho WC, Boudreault A, Durkin J, Gillard JW, Jaquith JB, Morris SJ, Barker PA. Mol Cell. 2008 Jun 20;30(6):689-700.

Smac mimetics and innate immune stimuli synergize to promote tumor death. - Smac mimetics and innate immune stimuli synergize to promote tumor death.

Beug ST, Tang VA, LaCasse EC, Cheung HH, Beauregard CE, Brun J, Nuyens JP, Earl N, St-Jean M, Holbrook J, Dastidar H, Mahoney DJ, Ilkow C, Le Boeuf F, Bell JC, Korneluk RG. Nat Biotechnol. 2014 Feb;32(2):182-90.

Cytoprotective effects of IAPs revealed by a small molecule antagonist. - Cytoprotective effects of IAPs revealed by a small molecule antagonist.

Galban S, Hwang C, Rumble JM, Oetjen KA, Wright CW, Boudreault A, Durkin J, Gillard JW, Jaquith JB, Morris SJ, Duckett CS. Biochem J. 2009 Feb 1;417(3):765-71.



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