Dimebon dihydrochloride

• Supplier: R&D Systems
• Catalog: 3201
• Prices: $105.00, $225.00
• Sizes: 1 mg, 10 mg
• Cas Number: 97657-92-6
• Chemical Name: 2,3,4,5-Tetrahydro-2,8-dimethyl-5-[2-(6-methyl-3-pyridinyl)ethyl]-1H-pyrido[4,3-b]indoledihydrochloride
• Formula: C21H25N3.2HCl
• Molecular Weight: 392.37
• Purity: >98%

Product References

Antihistamine agent Dimebon as a novel neuroprotector and a cognition enhancer. - Antihistamine agent Dimebon as a novel neuroprotector and a cognition enhancer.

Bachurin S, Bukatina E, Lermontova N, Tkachenko S, Afanasiev A, Grigoriev V, Grigorieva I, Ivanov Y, Sablin S, Zefirov N. Ann N Y Acad Sci. 2001 Jun;939:425-35.

Dimebolin is a 5-HT6 antagonist with acute cognition enhancing activities. - Dimebolin is a 5-HT6 antagonist with acute cognition enhancing activities.

Schaffhauser H, Mathiasen JR, Dicamillo A, Huffman MJ, Lu LD, McKenna BA, Qian J, Marino MJ. Biochem Pharmacol. 2009 Oct 15;78(8):1035-42.

Latrepirdine (dimebon) enhances autophagy and reduces intracellular GFP-Abeta42 - Latrepirdine (dimebon) enhances autophagy and reduces intracellular GFP-Abeta42

Bharadwaj PR, Verdile G, Barr RK, Gupta V, Steele JW, Lachenmayer ML, Yue Z, Ehrlich ME, Petsko G, Ju S, Ringe D, Sankovich SE, Caine JM, Macreadie IG, Gandy S, Martins RN. J Alzheimers Dis. 2012;32(4):949-67.