BMS 509744

• Supplier: R&D Systems
• Catalog: 5009
• Prices: $245.00
• Sizes: 10 mg
• Cas Number: 439575-02-7
• Chemical Name: N-[5-[[5-[(4-Acetyl-1-piperazinyl)carbonyl]-4-methoxy-2-methylphenyl]thio]-2-thiazolyl]-4-[[(1,2,2-trimethylpropyl)amino]methyl]benzamide
• Formula: C32H41N5O4S2
• Molecular Weight: 623.83
• Purity: >97%

Product References

Crystal structures of IL-2-inducible T cell kinase complexed with inhibitors: - Crystal structures of IL-2-inducible T cell kinase complexed with inhibitors:

Kutach AK, Villasenor AG, Lam D, Belunis C, Janson C, Lok S, Hong LN, Liu CM, Deval J, Novak TJ, Barnett JW, Chu W, Shaw D, Kuglstatter A. Chem Biol Drug Des. 2010 Aug;76(2):154-63.

Discovery and SAR of 2-amino-5-(thioaryl)thiazoles as potent and selective Itk - Discovery and SAR of 2-amino-5-(thioaryl)thiazoles as potent and selective Itk

Das J, Furch JA, Liu C, Moquin RV, Lin J, Spergel SH, McIntyre KW, Shuster DJ, O'Day KD, Penhallow B, Hung CY, Doweyko AM, Kamath A, Zhang H, Marathe P, Kanner SB, Lin TA, Dodd JH, Barrish JC, Wityak J. Bioorg Med Chem Lett. 2006 Jul 15;16(14):3706-12. Epub 2006 May 6.

Selective targeting of ITK blocks multiple steps of HIV replication. - Selective targeting of ITK blocks multiple steps of HIV replication.

Readinger JA, Schiralli GM, Jiang JK, Thomas CJ, August A, Henderson AJ, Schwartzberg PL. Proc Natl Acad Sci U S A. 2008 May 6;105(18):6684-9. doi: