ACPT-I

Name ACPT-I
Supplier Tocris Bioscience
Catalog 0187
Prices $199.00, $825.00
Sizes 10 mg, 50 mg
Function Type Agonist
Cas Number 194918-76-8
Chemical Name (1S,3R,4S)-1-Aminocyclopentane-1,3,4-tricarboxylicacid
Formula C8H11NO6
Molecular Weight 217.18
Description Agonist for group III mGlu receptors (EC 50 values are 7.2 and 8.2 μ M for mGlu 4a and mGlu 8 respectively). Anticonvulsant in mice.
Supplier Page Shop

Product References

Synthesis and pharmacological characterization of aminocyclopentanetricarboxylic - Synthesis and pharmacological characterization of aminocyclopentanetricarboxylic

Acher FC, Tellier FJ, Azerad R, Brabet IN, Fagni L, Pin JP. J Med Chem. 1997 Sep 12;40(19):3119-29.

Pharmacological characterization of the rat metabotropic glutamate receptor type - Pharmacological characterization of the rat metabotropic glutamate receptor type

De Colle C, Bessis AS, Bockaert J, Acher F, Pin JP. Eur J Pharmacol. 2000 Apr 7;394(1):17-26.

Anticonvulsant activity of a mGlu(4alpha) receptor selective agonist, - Anticonvulsant activity of a mGlu(4alpha) receptor selective agonist,

Chapman AG, Talebi A, Yip PK, Meldrum BS. Eur J Pharmacol. 2001 Jul 20;424(2):107-13.