AG 556

• Supplier: Tocris Bioscience
• Catalog: 0618
• Prices: $129.00, $535.00
• Sizes: 10 mg, 50 mg
• Function Type: Inhibitor
• Cas Number: 133550-41-1
• Chemical Name: (E)-2-Cyano-3-(3,4-dihydroxyphenyl)-N-(4-phenylbutyl)-2-propenamide
• Formula: C20H20N2O3
• Molecular Weight: 336.39
• Purity: >99 %
• Description: Epidermal growth factor receptor (EGFR) kinase inhibitor (IC 50 = 1.1 μ M). Selective over ErbB2 (IC 50 > 500 μ M).

Product References

Tyrphostins. 2. Heterocyclic and alpha-substituted benzylidenemalononitrile - Tyrphostins. 2. Heterocyclic and alpha-substituted benzylidenemalononitrile

Gazit A, Osherov N, Posner I, Yaish P, Poradosu E, Gilon C, Levitzki A. J Med Chem. 1991 Jun;34(6):1896-907.

Secondary dimerization between members of the epidermal growth factor receptor - Secondary dimerization between members of the epidermal growth factor receptor

Gamett DC, Pearson G, Cerione RA, Friedberg I. J Biol Chem. 1997 May 2;272(18):12052-6.