Agitoxin 2

Name Agitoxin 2
Supplier Tocris Bioscience
Catalog 2802
Prices $149.00
Sizes 10 µg
Function Type Blocker
Cas Number 168147-41-9
Formula C169H278N54O48S8
Molecular Weight 4090.87
Description Potent Shaker K + channel blocker (K i = 0.64 nM). Also inhibits K v 1.3, K v 1.6 and K v 1.1 K + channels (K i values are 4, 37 and 44 pM respectively).
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Product References

Purification and characterization of three inhibitors of voltage-dependent K+ - Purification and characterization of three inhibitors of voltage-dependent K+

Garcia ML, Garcia-Calvo M, Hidalgo P, Lee A, MacKinnon R. Biochemistry. 1994 Jun 7;33(22):6834-9.

Agitoxin footprinting the shaker potassium channel pore. - Agitoxin footprinting the shaker potassium channel pore.

Gross A, MacKinnon R. Neuron. 1996 Feb;16(2):399-406.

Recombinant expression of margatoxin and agitoxin-2 in Pichia pastoris: an - Recombinant expression of margatoxin and agitoxin-2 in Pichia pastoris: an

Anangi R, Koshy S, Huq R, Beeton C, Chuang WJ, King GF. PLoS One. 2012;7(12):e52965.