AGK 2

Name AGK 2
Supplier Tocris Bioscience
Catalog 5195
Prices $189.00, $765.00
Sizes 10 mg, 50 mg
Function Type Inhibitor
Cas Number 304896-28-4
Chemical Name 2-Cyano-3-[[5-(2,5-dichlorophenyl)-2-furanyl]-N-5-quinolinyl-2-propenamide
Formula C23H13Cl2N3O2
Molecular Weight 434.27
Purity >98 %
Description Selective inhibitor of SIRT2 (IC 50 = 3.5 μ M). Displays no activity at SIRT1 and SIRT3 at concentrations up to 40 μ M. Reduces α -synuclein-mediated toxicity in in vitro and in vivo models of Parkinson's disease.
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