Name | AGN 192403 hydrochloride |
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Supplier | Tocris Bioscience |
Catalog | 0842 |
Prices | $159.00, $665.00 |
Sizes | 10 mg, 50 mg |
Cas Number | 1021868-90-5 |
Chemical Name | (±)-2-endo-Amino-3-exo-isopropylbicyclo[2.2.1]heptanehydrochloride |
Formula | C10H19N.HCl |
Molecular Weight | 189.73 |
Description | I 1 imidazoline binding site selective ligand with a potency at I 1 comparable to moxonidine, but devoid of affinity for adrenoceptors and the I 2 binding site. Interestingly, in animal models, this compound causes none of the physiological responses associated with the I 1 binding site. |
Supplier Page | Shop |
Munk SA, Lai RK, Burke JE, Arasasingham PN, Kharlamb AB, Manlapaz CA, Padillo EU, Wijono MK, Hasson DW, Wheeler LA, Garst ME. J Med Chem. 1996 Mar 15;39(6):1193-5.
Raasch W, Schafer U, Qadri F, Dominiak P. Br J Pharmacol. 2002 Feb;135(3):663-72.
Mukaddam-Daher S, Menaouar A, Gutkowska J. Eur J Pharmacol. 2006 Jul 10;541(1-2):73-9. Epub 2006 May 12.