AI-3

Name AI-3
Supplier Tocris Bioscience
Catalog 5256
Prices $179.00, $745.00
Sizes 10 mg, 50 mg
Function Type Activator
Cas Number 882288-28-0
Chemical Name 1-Chloro-6,7-dihydro-6,6-dimethyl-3-(methylsulfonyl)-benzo[c]thiophen-4(5H)-one
Formula C11H13ClO3S2
Molecular Weight 292.8
Purity >98 %
Description Antioxidant response element (ARE) activator; disrupts Nrf2/Keap1 and Keap1/Cul3 interactions and stabilizes Nrf2. Activates ARE in an Nrf2 and PI 3-kinase dependent manner. Induces cytoprotective gene expression in vitro and in vivo .
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