AIDA

• Supplier: Tocris Bioscience
• Catalog: 2840
• Prices: $169.00, $705.00
• Sizes: 10 mg, 50 mg
• Function Type: Antagonist
• Cas Number: 168560-79-0
• Chemical Name: (RS)-1-Aminoindan-1,5-dicarboxylicacid
• Formula: C11H11NO4
• Molecular Weight: 221.21
• Purity: >98 %
• Description: A relatively potent and selective antagonist of group I metabotropic glutamate receptors (mGlu 1a ), having no effect on group II (mGlu 2 ) or group III (mGlu 4 ) receptors expressed individually in baby hamster kidney cells. Has no effect on ionotropic glutamate receptors. Centrally active following systemic administration in vivo .

Product References

1-Aminoindan-1,5-dicarboxylic acid: a novel antagonist at phospholipase C-linked - 1-Aminoindan-1,5-dicarboxylic acid: a novel antagonist at phospholipase C-linked

Pellicciari R, Luneia R, Costantino G, Marinozzi M, Natalini B, Jakobsen P, Kanstrup A, Lombardi G, Moroni F, Thomsen C. J Med Chem. 1995 Sep 15;38(19):3717-9.

Pharmacological characterization of 1-aminoindan-1,5-dicarboxylic acid, a potent - Pharmacological characterization of 1-aminoindan-1,5-dicarboxylic acid, a potent

Moroni F, Lombardi G, Thomsen C, Leonardi P, Attucci S, Peruginelli F, Torregrossa SA, Pellegrini-Giampietro DE, Luneia R, Pellicciari R. J Pharmacol Exp Ther. 1997 May;281(2):721-9.

Class I mGlu receptor antagonist 1-aminoindan-1,5-dicarboxylic acid blocks - Class I mGlu receptor antagonist 1-aminoindan-1,5-dicarboxylic acid blocks

Nielsen KS, Macphail EM, Riedel G. Eur J Pharmacol. 1997 May 20;326(2-3):105-8.