(+)-AJ 76 hydrochloride

Name (+)-AJ 76 hydrochloride
Supplier Tocris Bioscience
Catalog 4946
Prices $155.00, $645.00
Sizes 10 mg, 50 mg
Function Type Antagonist
Cas Number 85378-82-1
Chemical Name (1S,2R)-cis-5-Methoxy-1-methyl-2-(N-propylamino)tetralinhydrochloride
Formula C15H23NO.HCl
Molecular Weight 269.81
Description Dopamine receptor antagonist with preferential action at presynaptic receptors (pK i values are 6.95, 6.67, 6.37, 6.21 and 6.07 at hD 3 . hD 4 , hD 2S , hD 2L and rD 2 receptors respectively).
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Product References

Resolved cis- and trans-2-amino-5-methoxy-1-methyltetralins: central dopamine - Resolved cis- and trans-2-amino-5-methoxy-1-methyltetralins: central dopamine

Johansson AM, Arvidsson LE, Hacksell U, Nilsson JL, Svensson K, Carlsson A. J Med Chem. 1987 Apr;30(4):602-11.

Effects of repeated administration of the preferential dopamine autoreceptor - Effects of repeated administration of the preferential dopamine autoreceptor

Kullingsjo H, Carlsson A, Svensson K. Eur J Pharmacol. 1991 Dec 3;205(3):241-6.

Intracerebral infusion of (+)-AJ76 and (+)-UH232: effects on dopamine release and - Intracerebral infusion of (+)-AJ76 and (+)-UH232: effects on dopamine release and

Waters N, Hansson L, Lofberg L, Carlsson A. Eur J Pharmacol. 1994 Jan 14;251(2-3):181-90.

The role of dopamine D3 compared with D2 receptors in the control of locomotor - The role of dopamine D3 compared with D2 receptors in the control of locomotor

Millan MJ, Seguin L, Gobert A, Cussac D, Brocco M. Psychopharmacology (Berl). 2004 Jul;174(3):341-57. Epub 2004 Feb 19.