| Name | Akti-1/2 |
|---|---|
| Supplier | Tocris Bioscience |
| Catalog | 1353 |
| Prices | $155.00, $645.00 |
| Sizes | 10 mg, 50 mg |
| Function Type | Inhibitor |
| Cas Number | 612847-09-3 |
| Chemical Name | 1,3-Dihydro-1-[1-[[4-(6-phenyl-1H-imidazo[4,5-g]quinoxalin-7-yl)phenyl]methyl]-4-piperidinyl]-2H-benzimidazol-2-one |
| Formula | C34N29N7O |
| Molecular Weight | 551.64 |
| Purity | >98 % |
| Description | Potent and selective dual Akt1 and 2 inhibitor (IC 50 values are 50 and 210 nM, respectively). Selective for Akt1 and 2 over a panel of other tyrosine and serine/threonine kinases. Sensitizes LnCaP cells to TRAIL (TNF-related apoptosis-inducing ligand) induced apoptosis. Active in vivo . |
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