Alantolactone

Name Alantolactone
Supplier Tocris Bioscience
Catalog 0205
Prices $189.00, $765.00
Sizes 10 mg, 50 mg
Cas Number 546-43-0
Chemical Name (3aR,5S,8aR,9aR)-3a,5,6,7,8,8a,9,9a-Octahydro-5,8a-dimethyl-3-methylenenaphtho[2,3-b]furan-2(3H)-one
Formula C15H20O2
Molecular Weight 232.32
Purity >98 %
Description Sesquiterpene lactone. Induces activin/SMAD3 signaling and disrupts Cripto-1/activin receptor type II A interaction. Displays antiproliferative activity in human colon adenocarcinoma HCT-8 cells.
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Product References

Toxic effect of alantolactone and dihydroalantolactone in in vitro cultures of - Toxic effect of alantolactone and dihydroalantolactone in in vitro cultures of

Dupuis G, Brisson J. Chem Biol Interact. 1976 Nov;15(3):205-17.

Activation of caspases and poly (ADP-ribose) polymerase cleavage to induce - Activation of caspases and poly (ADP-ribose) polymerase cleavage to induce

Pal HC, Sehar I, Bhushan S, Gupta BD, Saxena AK. Toxicol In Vitro. 2010 Sep;24(6):1599-609.

Alantolactone inhibits cell proliferation by interrupting the interaction between - Alantolactone inhibits cell proliferation by interrupting the interaction between

Shi Y, Bao YL, Wu Y, Yu CL, Huang YX, Sun Y, Zheng LH, Li YX. J Biomol Screen. 2011 Jun;16(5):525-35.