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AS 19

Name AS 19
Supplier Tocris Bioscience
Catalog 4927
Prices $189.00, $765.00
Sizes 10 mg, 50 mg
Function Type Agonist
Cas Number 1000578-26-6
Chemical Name (2S)-(+)-5-(1,3,5-Trimethylpyrazol-4-yl)-2-(dimethylamino)tetralin
Formula C18H25N3
Molecular Weight 283.41
Purity >98 %
Description Potent 5-HT 7 receptor agonist (IC 50 = 0.83 nM). Enhances memory consolidation and reverses scopolamine- or dizocilpine-induced amnesia in vivo .
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Product References

Effects of the potential 5-HT7 receptor agonist AS 19 in an autoshaping learning - Effects of the potential 5-HT7 receptor agonist AS 19 in an autoshaping learning

Perez-Garcia GS, Meneses A. Behav Brain Res. 2005 Aug 30;163(1):136-40.

An mRNA expression analysis of stimulation and blockade of 5-HT7 receptors during - An mRNA expression analysis of stimulation and blockade of 5-HT7 receptors during

Perez-Garcia G, Gonzalez-Espinosa C, Meneses A. Behav Brain Res. 2006 Apr 25;169(1):83-92. Epub 2006 Feb 9.

The role of 5-hydroxytryptamine 7 receptors in the phencyclidine-induced novel - The role of 5-hydroxytryptamine 7 receptors in the phencyclidine-induced novel

Horiguchi M, Huang M, Meltzer HY. J Pharmacol Exp Ther. 2011 Aug;338(2):605-14.



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