ASP 2535

Name ASP 2535
Supplier Tocris Bioscience
Catalog 3737
Prices $235.00
Sizes 10 mg
Function Type Inhibitor
Cas Number 374886-51-8
Chemical Name 4-[3-(1-Methylethyl)-5-(6-phenyl-3-pyridinyl)-4H-1,2,4-triazol-4-yl]-2,1,3-benzoxadiazole
Formula C22H18N6O
Molecular Weight 382.42
Purity >98 %
Description Potent and selective GlyT1 inhibitor (IC 50 = 92 nM). Exhibits 50-fold selectivity over GlyT2. Attenuates MK 801 -induced working memory deficits and PCP -induced visual learning deficits in mice. Orally available and brain penetrant.
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