AY-NH 2

• Supplier: Tocris Bioscience
• Catalog: 1639
• Prices: $269.00
• Sizes: 1 mg
• Function Type: Agonist
• Cas Number: 352017-71-1
• Formula: C34H48N8O7
• Molecular Weight: 680.8
• Description: Selective PAR 4 receptor agonist peptide. Stimulates platelet aggregation in vitro (EC 50 = 15 μ M). Exhibits an increase in paw thickness in the paw edema inflammation model in vivo .

Product References

Structure-function analysis of protease-activated receptor 4 tethered ligand - Structure-function analysis of protease-activated receptor 4 tethered ligand

Faruqi TR, Weiss EJ, Shapiro MJ, Huang W, Coughlin SR. J Biol Chem. 2000 Jun 30;275(26):19728-34.

Proteinase-activated receptor 4 (PAR4): activation and inhibition of rat platelet - Proteinase-activated receptor 4 (PAR4): activation and inhibition of rat platelet

Hollenberg MD, Saifeddine M. Can J Physiol Pharmacol. 2001 May;79(5):439-42.

Proteinase-activated receptor-4: evaluation of tethered ligand-derived peptides - Proteinase-activated receptor-4: evaluation of tethered ligand-derived peptides

Hollenberg MD, Saifeddine M, Sandhu S, Houle S, Vergnolle N. Br J Pharmacol. 2004 Oct;143(4):443-54. Epub 2004 Sep 27.