| Name | AZ 12080282 dihydrochloride |
|---|---|
| Supplier | Tocris Bioscience |
| Catalog | 3317 |
| Prices | $219.00, $905.00 |
| Sizes | 10 mg, 50 mg |
| Function Type | Inhibitor |
| Chemical Name | N-[5-(1H-Imidazol-2-yl)-2-methylphenyl]-4-(2-pyridinylmethoxy)benzamidedihydrochloride |
| Formula | C23H20N4O2.2HCl |
| Molecular Weight | 457.35 |
| Purity | >98 % |
| Description | Inhibitor of Hedgehog (Hh) signaling (IC 50 <0.012 μ M in a firefly reporter assay against the Hh pathway). Shown to displace cyclopamine in HeLa cells expressing Smoothened. Exhibits selectivity against p38 α . Orally bioavailable. |
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