AZ 12216052

• Supplier: Tocris Bioscience
• Catalog: 4838
• Prices: $149.00, $629.00
• Sizes: 10 mg, 50 mg
• Function Type: Modulator
• Cas Number: 1290628-31-7
• Chemical Name: 2-[[(4-Bromophenyl)methyl]thio]-N-[4-(1-methylpropyl)phenyl]acetamide
• Formula: C19H22BrNOS
• Molecular Weight: 392.35
• Purity: >98 %
• Description: Positive allosteric modulator at mGlu 8 receptors. Exhibits anxiolytic effects in mouse models of anxiety.

Product References

Acute pharmacological modulation of mGluR8 reduces measures of anxiety. - Acute pharmacological modulation of mGluR8 reduces measures of anxiety.

Duvoisin RM, Pfankuch T, Wilson JM, Grabell J, Chhajlani V, Brown DG, Johnson E, Raber J. Behav Brain Res. 2010 Oct 15;212(2):168-73.

Opposing roles of mGluR8 in measures of anxiety involving non-social and social - Opposing roles of mGluR8 in measures of anxiety involving non-social and social

Duvoisin RM, Villasana L, Davis MJ, Winder DG, Raber J. Behav Brain Res. 2011 Aug 1;221(1):50-4.