| Name | AZ 20 |
|---|---|
| Supplier | Tocris Bioscience |
| Catalog | 5232 |
| Prices | $255.00, $1,045.00 |
| Sizes | 10 mg, 50 mg |
| Function Type | Inhibitor |
| Cas Number | 1233339-22-4 |
| Chemical Name | 4-[4-[(3R)-3-Methyl-4-morpholinyl]-6-[1-(methylsulfonyl)cyclopropyl]-2-pyrimidinyl]-1H-indole |
| Formula | C21H24N4O3S |
| Molecular Weight | 412.51 |
| Purity | >98 % |
| Description | Potent and selective ATR kinase inhibitor (IC 50 = 5 nM). Exhibits 7.6-fold selectivity over mTOR and selectivity over a panel of 442 kinases, including ATM kinase, PI3-K isoforms, and DNA-PK. Inhibits cell growth in cell lines with high baseline levels of replication stress. Displays antitumor effects in vivo . |
| Supplier Page | Shop |