| Name | AZ 6102 |
|---|---|
| Supplier | Tocris Bioscience |
| Catalog | 3994 |
| Prices | $199.00, $825.00 |
| Sizes | 10 mg, 50 mg |
| Function Type | Inhibitor |
| Cas Number | 1645286-75-4 |
| Chemical Name | rel-2-[4-[6-[(3R,5S)-3,5-Dimethyl-1-piperazinyl]-4-methyl-3-pyridinyl]phenyl]-3,7-dihydro-7-methyl-4H-pyrrolo[2,3-d]pyrimidin-4-one |
| Formula | C25H28N6O |
| Molecular Weight | 428.53 |
| Purity | >98 % |
| Description | Potent TNKS2 and TNKS1 inhibitor (IC 50 values are 1 and 3 nM, respectively). Exhibits >100-fold selectivity for TNKS1/2 over PARP-1, PARP-2 and PARP-6. Inhibits Wnt signaling in DLD-1 cells (IC 50 = 5 nM). Exhibits moderate oral bioavailability. |
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