AZ Dyrk1B 33

• Supplier: Tocris Bioscience
• Catalog: 4836
• Prices: $259.00
• Sizes: 10 mg
• Function Type: Inhibitor
• Cas Number: 1679330-37-0
• Chemical Name: 3-(2-Methyl-4-pyrimidinyl)-1-(phenylmethyl)-1H-pyrrolo[2,3-c]pyridine
• Formula: C19H16N4
• Molecular Weight: 300.36
• Purity: >98 %
• Description: Potent and selective ATP-competitive Dyrk1B kinase inhibitor (IC 50 = 7 nM); displays distinct cellular effects when compared to DYRK1B knockdown through siRNA. Demonstrates cellular in vitro activity (IC 50 = 194 nM). Exhibits better selectivity than AZ 191 (Cat. No 5232); displays no off-target effects against a panel of 124 kinases tested (no kinase was inhibited above 50% at 1 μ M).

Product References

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