BMS 453

• Supplier: Tocris Bioscience
• Catalog: 4806
• Prices: $199.00
• Sizes: 10 mg
• Cas Number: 166977-43-1
• Chemical Name: 4-[(1E)-2-(5,6-Dihydro-5,5-dimethyl-8-phenyl-2-naphthalenyl)ethenyl]-benzoicacid
• Formula: C27H24O2
• Molecular Weight: 380.48
• Purity: >98 %
• Description: Synthetic retinoid. Retinoic acid receptor β (RAR β ) agonist in vivo ; RAR α and RAR γ antagonist in vitro . Inhibits breast cell proliferation by inducing active transforming growth factor β (TGF β ) and causes G 1 arrest.

Product References

RAR-specific agonist/antagonists which dissociate transactivation and AP1 - RAR-specific agonist/antagonists which dissociate transactivation and AP1

Chen JY, Penco S, Ostrowski J, Balaguer P, Pons M, Starrett JE, Reczek P, Chambon P, Gronemeyer H. EMBO J. 1995 Mar 15;14(6):1187-97.

The retinoic acid receptor antagonist, BMS453, inhibits normal breast cell growth - The retinoic acid receptor antagonist, BMS453, inhibits normal breast cell growth

Yang L, Ostrowski J, Reczek P, Brown P. Oncogene. 2001 Nov 29;20(55):8025-35.

Commitment of mouse embryonic stem cells to the adipocyte lineage requires - Commitment of mouse embryonic stem cells to the adipocyte lineage requires

Monteiro MC, Wdziekonski B, Villageois P, Vernochet C, Iehle C, Billon N, Dani C. Stem Cells Dev. 2009 Apr;18(3):457-63.