Cantharidin

• Supplier: Tocris Bioscience
• Catalog: 3281
• Prices: $129.00
• Sizes: 50 mg
• Function Type: Inhibitor
• Cas Number: 56-25-7
• Chemical Name: (3aα,4β,7β,7aα)-Hexahydro-3a,7a-dimethyl-4,7-epoxyisobenzofuran-1,3-dione
• Formula: C10H12O4
• Molecular Weight: 196.2
• Description: Natural toxin inhibitor of protein phosphatases 1 and 2A (K i values are 1.1 and 0.19 μ M respectively); similar to okadaic acid (Cat. No. 1136). Displays > 500-fold selectivity over PP2B.

Product References

Cantharidin, another natural toxin that inhibits the activity of serine/threonine - Cantharidin, another natural toxin that inhibits the activity of serine/threonine

Honkanen RE. FEBS Lett. 1993 Sep 20;330(3):283-6.

Cantharidin effects on protein phosphatases and the phosphorylation state of - Cantharidin effects on protein phosphatases and the phosphorylation state of

Eldridge R, Casida JE. Toxicol Appl Pharmacol. 1995 Jan;130(1):95-100.

The protein phosphatase inhibitor cantharidin alters vascular endothelial cell - The protein phosphatase inhibitor cantharidin alters vascular endothelial cell

Knapp J, Boknik P, Luss I, Huke S, Linck B, Luss H, Muller FU, Muller T, Nacke P, Noll T, Piper HM, Schmitz W, Vahlensieck U, Neumann J. J Pharmacol Exp Ther. 1999 Jun;289(3):1480-6.