CD 2665

• Supplier: Tocris Bioscience
• Catalog: 3824
• Prices: $199.00, $825.00
• Sizes: 10 mg, 50 mg
• Function Type: Antagonist
• Cas Number: 170355-78-9
• Chemical Name: 4-[6-[(2-Methoxyethoxy)methoxy]-7-tricyclo[3.3.1.13,7]dec-1-yl-2-naphthalenyl)benzoicacid
• Formula: C31H34O5
• Molecular Weight: 486.6
• Purity: >98 %
• Description: Selective RAR βγ antagonist (K D values are 110, 306 and > 1000 nM for RAR γ , RAR β and RAR α respectively). Blocks retinoic acid-induced apoptosis ex vivo .

Product References

Induction of apoptosis by retinoids and retinoic acid receptor gamma-selective - Induction of apoptosis by retinoids and retinoic acid receptor gamma-selective

Szondy Z, Reichert U, Bernardon JM, Michel S, Toth R, Ancian P, Ajzner E, Fesus L. Mol Pharmacol. 1997 Jun;51(6):972-82.

Antiproliferative activity and apoptosis induced by retinoic acid receptor-gamma - Antiproliferative activity and apoptosis induced by retinoic acid receptor-gamma

Meister B, Fink FM, Hittmair A, Marth C, Widschwendter M. Anticancer Res. 1998 May-Jun;18(3A):1777-86.

The role of specific retinoid receptors in sebocyte growth and differentiation in - The role of specific retinoid receptors in sebocyte growth and differentiation in

Kim MJ, Ciletti N, Michel S, Reichert U, Rosenfield RL. J Invest Dermatol. 2000 Feb;114(2):349-53.