Ceefourin 1

• Supplier: Tocris Bioscience
• Catalog: 4793
• Prices: $149.00, $629.00
• Sizes: 10 mg, 50 mg
• Function Type: Inhibitor
• Cas Number: 315702-40-0
• Chemical Name: 5-[(2-Benzothiazolylthio)methyl]-2,4-dihydro-4-methyl-3H-1,2,4-triazole-3-thione
• Formula: C11H10N4S3
• Molecular Weight: 294.42
• Purity: >98 %
• Description: Selective MRP (multidrug resistance-associated protein) 4 inhibitor (IC 50 = 2.6 μ M). Selective for MRP4 over P-gp, MRP1 and ABCG2. Sensitizes MRP4 over-expressing cells to SN 38 (Cat. No. 2684).

Product References

Beta-lactam antibiotics offer neuroprotection by increasing glutamate transporter - Beta-lactam antibiotics offer neuroprotection by increasing glutamate transporter

Rothstein JD, Patel S, Regan MR, Haenggeli C, Huang YH, Bergles DE, Jin L, Dykes Hoberg M, Vidensky S, Chung DS, Toan SV, Bruijn LI, Su ZZ, Gupta P, Fisher PB. Nature. 2005 Jan 6;433(7021):73-7.

Neuroprotective potential of ceftriaxone in in vitro models of stroke. - Neuroprotective potential of ceftriaxone in in vitro models of stroke.

Lipski J, Wan CK, Bai JZ, Pi R, Li D, Donnelly D. Neuroscience. 2007 May 11;146(2):617-29. Epub 2007 Mar 23.

The beta-lactam antibiotic, ceftriaxone, attenuates morphine-evoked hyperthermia - The beta-lactam antibiotic, ceftriaxone, attenuates morphine-evoked hyperthermia

Rawls SM, Tallarida R, Robinson W, Amin M. Br J Pharmacol. 2007 Aug;151(7):1095-102. Epub 2007 Jun 25.