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CGP 37849

Name CGP 37849
Supplier Tocris Bioscience
Catalog 1114
Prices $199.00, $825.00
Sizes 10 mg, 50 mg
Function Type Antagonist
Cas Number 127910-31-0
Chemical Name (E)-(±)-2-Amino-4-methyl-5-phosphono-3-pentenoicacid
Formula C6H12NO5P
Molecular Weight 209.14
Purity >99 %
Description Potent, selective and competitive NMDA receptor antagonist (K i = 35 nM). Anticonvulsive following oral administration in vivo .
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Product References

CGP 37849 and CGP 39551: novel and potent competitive N-methyl-D-aspartate - CGP 37849 and CGP 39551: novel and potent competitive N-methyl-D-aspartate

Fagg GE, Olpe HR, Pozza MF, Baud J, Steinmann M, Schmutz M, Portet C, Baumann P, Thedinga K, Bittiger H, et al.. Br J Pharmacol. 1990 Apr;99(4):791-7.

Electrophysiological characterization of a novel potent and orally active NMDA - Electrophysiological characterization of a novel potent and orally active NMDA

Pozza MF, Olpe HR, Brugger F, Fagg GE. Eur J Pharmacol. 1990 Jun 21;182(1):91-100.

Anticonvulsant and behavioral effects of two novel competitive - Anticonvulsant and behavioral effects of two novel competitive

Loscher W, Honack D. J Pharmacol Exp Ther. 1991 Feb;256(2):432-40.



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