ω -Conotoxin GVIA

Name ω -Conotoxin GVIA
Supplier Tocris Bioscience
Catalog 3124
Prices $329.00
Sizes 250 µg
Cas Number 106375-28-4
Formula C120H182N38O43S6
Molecular Weight 3037
Description Peptide neurotoxin; selectively and reversibly blocks N-type calcium channels (IC 50 = 0.15 nM). Reduces ( RS )-3,5-DHPG (Cat. No. 0342)-induced long term depression in vivo .
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Product References

Multiple types of neuronal calcium channels and their selective modulation. - Multiple types of neuronal calcium channels and their selective modulation.

Tsien RW, Lipscombe D, Madison DV, Bley KR, Fox AP. Trends Neurosci. 1988 Oct;11(10):431-8.

Role of basic residues for the binding of omega-conotoxin GVIA to N-type calcium - Role of basic residues for the binding of omega-conotoxin GVIA to N-type calcium

Sato K, Park NG, Kohno T, Maeda T, Kim JI, Kato R, Takahashi M. Biochem Biophys Res Commun. 1993 Aug 16;194(3):1292-6.

Prolonged cardiovascular effects of the N-type Ca2+ channel antagonist - Prolonged cardiovascular effects of the N-type Ca2+ channel antagonist

Wright CE, Angus JA. J Cardiovasc Pharmacol. 1997 Sep;30(3):392-9.

Distinct mechanisms contribute to agonist and synaptically induced metabotropic - Distinct mechanisms contribute to agonist and synaptically induced metabotropic

Connelly T, Fan Y, Schulz PE. Eur J Pharmacol. 2011 Sep 30;667(1-3):160-8.