Cortistatin-8

• Supplier: Tocris Bioscience
• Catalog: 3374
• Prices: $199.00
• Sizes: 1 mg
• Cas Number: 485803-62-1
• Formula: C47H68N12O9S2
• Molecular Weight: 1009.25
• Description: Synthetic cortistatin analog that lacks the ability to bind somatostatin receptors but retains ghrelin receptor binding. Acts as a ghrelin receptor antagonist; counteracts the response of ghrelin on gastric acid secretion.

Product References

Cortistatin mimics somatostatin by inducing a dual, dose-dependent stimulatory - Cortistatin mimics somatostatin by inducing a dual, dose-dependent stimulatory

Luque RM, Peinado JR, Gracia-Navarro F, Broglio F, Ghigo E, Kineman RD, Malagon MM, Castano JP. J Mol Endocrinol. 2006 Jun;36(3):547-56.

Evidence for a role of the GHS-R1a receptors in ghrelin inhibition of gastric - Evidence for a role of the GHS-R1a receptors in ghrelin inhibition of gastric

Sibilia V, Muccioli G, Deghenghi R, Pagani F, De Luca V, Rapetti D, Locatelli V, Netti C. J Neuroendocrinol. 2006 Feb;18(2):122-8.

Cortistatin-8, a synthetic cortistatin-derived ghrelin receptor ligand, does not - Cortistatin-8, a synthetic cortistatin-derived ghrelin receptor ligand, does not

Prodam F, Benso A, Gramaglia E, Lucatello B, Riganti F, van der Lely AJ, Deghenghi R, Muccioli G, Ghigo E, Broglio F. Neuropeptides. 2008 Feb;42(1):89-93. Epub 2007 Dec 3.