NBQX

• Supplier: Abcam
• Catalog: ab120045
• Cas Number: 118876-58-7
• Pubchem: 3272524
• Chemical Name: 2,3-Dioxo-6-nitro-1,2,3,4-tetrahydrobenzo[f]quinoxaline-7-sulfonamide
• Formula: C12H8N4O6S
• Molecular Weight: 336.28
• Purity: > 99%
• Description: AMPA / kainate antagonist

Product images

ab96379 staining MEK1 (phospho S298) in SK-N-SH cells treated with NBQX (ab120045), by ICC/IF. Decrease in MEK1 (phospho S298) expression correlates with increased concentration of NBQX, as described in literature.The cells were incubated at 37°C for 1h in media containing different concentrations of ab120045 (NBQX) in DMSO, fixed with 4% formaldehyde for 10 minutes at room temperature and blocked with PBS containing 10% goat serum, 0.3 M glycine, 1% BSA and 0.1% tween for 2h at room temperature. Staining of the treated cells with ab96379 (1/100 dilution) was performed overnight at 4°C in PBS containing 1% BSA and 0.1% tween. A DyLight 488 goat anti-rabbit polyclonal antibody (ab96899) at 1/250 dilution was used as the secondary antibody.

Product References

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Long-term depression of synaptic kainate receptors reduces excitability by - Long-term depression of synaptic kainate receptors reduces excitability by

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Strengthening the accumbal indirect pathway promotes resilience to compulsive - Strengthening the accumbal indirect pathway promotes resilience to compulsive

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Small-conductance Ca2+-activated K+ channels modulate action potential-induced - Small-conductance Ca2+-activated K+ channels modulate action potential-induced

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Rapid, activity-independent turnover of vesicular transmitter content at a mixed - Rapid, activity-independent turnover of vesicular transmitter content at a mixed

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