Nifedipine
| Name | Nifedipine |
|---|---|
| Supplier | Abcam |
| Catalog | ab120135 |
| Cas Number | 21829-25-4 |
| Pubchem | 4485 |
| Chemical Name | 1,4-Dihydro-2,6-dimethyl-4-(2-nitrophenyl)-3,5-pyridinedicarboxylic acid dimethyl ester |
| Formula | C17H18N2O6 |
| Molecular Weight | 346.34 |
| Purity | > 99% |
| Description | L-type Ca2+ channel blocker |
| Supplier Page | Shop |
Product images
ab2770 staining aryl hydrocarbon receptor in MDA-MB-231 cells treated with nifedipine (ab120135), by ICC/IF. Increase in aryl hydrocarbon receptor expression correlates with increased concentration of nifedipine, as described in literature.The cells were incubated at 37°C for 6h in media containing different concentrations of ab120135 (nifedipine) in DMSO, fixed with 100% methanol for 5 minutes at -20°C and blocked with PBS containing 10% goat serum, 0.3 M glycine, 1% BSA and 0.1% tween for 2h at room temperature. Staining of the treated cells with ab2770 (1/100 dilution) was performed overnight at 4°C in PBS containing 1% BSA and 0.1% tween. A DyLight 488 goat anti-mouse polyclonal antibody (ab96879) at 1/250 dilution was used as the secondary antibody. Nuclei were counterstained with DAPI and are shown in blue.
Product References
Mossy fiber-evoked subthreshold responses induce timing-dependent plasticity at - Mossy fiber-evoked subthreshold responses induce timing-dependent plasticity at
Brandalise F, Gerber U. Proc Natl Acad Sci U S A. 2014 Mar 18;111(11):4303-8. doi:
Depression biased non-Hebbian spike-timing-dependent synaptic plasticity in the - Depression biased non-Hebbian spike-timing-dependent synaptic plasticity in the
Pandey A, Sikdar SK. J Physiol. 2014 Aug 15;592(Pt 16):3537-57.
Identification of CaV channel types expressed in muscle afferent neurons. - Identification of CaV channel types expressed in muscle afferent neurons.
Ramachandra R, Hassan B, McGrew SG, Dompor J, Farrag M, Ruiz-Velasco V, Elmslie KS. J Neurophysiol. 2013 Oct;110(7):1535-43.