NMDA
| Name | NMDA |
|---|---|
| Supplier | Abcam |
| Catalog | ab120052 |
| Cas Number | 6384-92-5 |
| Pubchem | 22880 |
| Chemical Name | (R)-2-(Methylamino)succinic acid |
| Formula | C5H9NO4 |
| Molecular Weight | 147.13 |
| Purity | > 99% |
| Description | Excitotoxic amino acid |
| Supplier Page | Shop |
Product images
ab55051 staining GABA B receptor 1 in SK-N-SH cells treated with NMDA (ab120052), by ICC/IF. Internalization of GABA B receptor 1 correlates with increased concentration of NMDA, as described in literature.The cells were incubated at 37°C for 30 minutes in media containing different concentrations of ab120052 (NMDA) in DMSO, fixed with 4% formaldehyde for 10 minutes at room temperature and blocked with PBS containing 10% goat serum, 0.3 M glycine, 1% BSA and 0.1% tween for 2h at room temperature. Staining of the treated cells with ab55051 (1 µg/ml) was performed overnight at 4°C in PBS containing 1% BSA and 0.1% tween. A DyLight 488 goat anti-mouse polyclonal antibody (ab96879) at 1/250 dilution was used as the secondary antibody. Nuclei were counterstained with DAPI and are shown in blue.
Product References
Hilar somatostatin interneurons contribute to synchronized GABA activity in an in - Hilar somatostatin interneurons contribute to synchronized GABA activity in an in
Grosser S, Queenan BN, Lalchandani RR, Vicini S. PLoS One. 2014 Jan 21;9(1):e86250.
Critical role of increased PTEN nuclear translocation in excitotoxic and ischemic - Critical role of increased PTEN nuclear translocation in excitotoxic and ischemic
Zhang S, Taghibiglou C, Girling K, Dong Z, Lin SZ, Lee W, Shyu WC, Wang YT. J Neurosci. 2013 May 1;33(18):7997-8008.
Sleep-wake sensitive mechanisms of adenosine release in the basal forebrain of - Sleep-wake sensitive mechanisms of adenosine release in the basal forebrain of
Sims RE, Wu HH, Dale N. PLoS One. 2013;8(1):e53814.
The type II cGMP dependent protein kinase regulates GluA1 levels at the plasma - The type II cGMP dependent protein kinase regulates GluA1 levels at the plasma
Incontro S, Ciruela F, Ziff E, Hofmann F, Sanchez-Prieto J, Torres M. Biochim Biophys Acta. 2013 Aug;1833(8):1820-31. doi:
Riluzole attenuates the effects of chemoconvulsants acting on glutamatergic and - Riluzole attenuates the effects of chemoconvulsants acting on glutamatergic and
Ramakrishnan L, Dalhoff Z, Fettig SL, Eggerichs MR, Nelson BE, Shrestha B, Elshikh AH, Karki P. Eur J Pharmacol. 2013 Oct 15;718(1-3):493-501.
Activity-dependent regulation of the K/Cl transporter KCC2 membrane diffusion, - Activity-dependent regulation of the K/Cl transporter KCC2 membrane diffusion,
Chamma I, Heubl M, Chevy Q, Renner M, Moutkine I, Eugene E, Poncer JC, Levi S. J Neurosci. 2013 Sep 25;33(39):15488-503.
Contributions of area Te2 to rat recognition memory. - Contributions of area Te2 to rat recognition memory.
Ho JW, Narduzzo KE, Outram A, Tinsley CJ, Henley JM, Warburton EC, Brown MW. Learn Mem. 2011 Jun 23;18(7):493-501.
Young age and low temperature, but not female gender delay ATP loss and glutamate - Young age and low temperature, but not female gender delay ATP loss and glutamate
Mohr C, Brady JD, Rossi DJ. Neuropharmacology. 2010 Feb;58(2):392-403.
Protein SUMOylation modulates calcium influx and glutamate release from - Protein SUMOylation modulates calcium influx and glutamate release from
Feligioni M, Nishimune A, Henley JM. Eur J Neurosci. 2009 Apr;29(7):1348-56.