(R,S)-3,5-DHPG
| Name | (R,S)-3,5-DHPG |
|---|---|
| Supplier | Abcam |
| Catalog | ab120020 |
| Cas Number | 19641-83-9 |
| Pubchem | 108001 |
| Chemical Name | (R,S)-3,5-Dihydroxyphenylglycine |
| Formula | C8H9NO4 |
| Molecular Weight | 183.16 |
| Purity | > 98% |
| Description | Group I mGlu receptor agonist |
| Supplier Page | Shop |
Product images
ab17722 staining FMRP in SK-N-SH cells treated with (R,S)-3,5-DHPG (ab120020), by ICC/IF. Increase in FMRP expression correlates with increased concentration of (R,S)-3,5-DHPG, as described in literature.The cells were incubated at 37°C for 1h in media containing different concentrations of ab120020 ((R,S)-3,5-DHPG) in DMSO, fixed with 4% formaldehyde for 10 minutes at room temperature and blocked with PBS containing 10% goat serum, 0.3 M glycine, 1% BSA and 0.1% tween for 2h at room temperature. Staining of the treated cells with ab17722 (5 µg/ml) was performed overnight at 4°C in PBS containing 1% BSA and 0.1% tween. A DyLight 488 goat anti-rabbit polyclonal antibody (ab96899) at 1/250 dilution was used as the secondary antibody. Nuclei were counterstained with DAPI and are shown in blue.
Product References
Regulation of increased glutamatergic input to spinal dorsal horn neurons by - Regulation of increased glutamatergic input to spinal dorsal horn neurons by
Li JQ, Chen SR, Chen H, Cai YQ, Pan HL. J Neurochem. 2010 Jan;112(1):162-72.
Homer 1a gates the induction mechanism for endocannabinoid-mediated synaptic - Homer 1a gates the induction mechanism for endocannabinoid-mediated synaptic
Roloff AM, Anderson GR, Martemyanov KA, Thayer SA. J Neurosci. 2010 Feb 24;30(8):3072-81.
Presynaptic mGlu1 and mGlu5 autoreceptors facilitate glutamate exocytosis from - Presynaptic mGlu1 and mGlu5 autoreceptors facilitate glutamate exocytosis from
Musante V, Neri E, Feligioni M, Puliti A, Pedrazzi M, Conti V, Usai C, Diaspro A, Ravazzolo R, Henley JM, Battaglia G, Pittaluga A. Neuropharmacology. 2008 Sep;55(4):474-82.