Tetrodotoxin citrate
| Name | Tetrodotoxin citrate |
|---|---|
| Supplier | Abcam |
| Catalog | ab120055 |
| Cas Number | 18660-81-6 |
| Chemical Name | Octahydro-12-(hydroxymethyl)-2-imino-5,9:7,10a-dimethano-10aH-[1,3]dioxocino[6,5-d] pyrimidine-4,7,10,11,12-pentol + citrate buffer |
| Formula | C11H17N3O8 |
| Molecular Weight | 319.27 |
| Purity | > 98% |
| Description | Na+ channel blocker; water-soluble |
| Supplier Page | Shop |
Product images
Cell-attached recording of a striatal cholinergic interneuron depicting TTX (100 nM) inhibition of spontaneous action potential firing. The open bar indicates time of TTX application.
Quantification of the p-S6rp signal in each striatal ChAt immunoreactive neuron after 1 hour incubation in control or TTX (1 M). Each dot corresponds to one neuron; each color corresponds to a different animal; dashed lines indicate the mean. Fluorescence values are normalized in arbitrary units (a.u.).
Product References
Optogenetic evocation of field inhibitory postsynaptic potentials in hippocampal - Optogenetic evocation of field inhibitory postsynaptic potentials in hippocampal
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Confirmation and distribution of tetrodotoxin for the first time in terrestrial - Confirmation and distribution of tetrodotoxin for the first time in terrestrial
Stokes AN, Ducey PK, Neuman-Lee L, Hanifin CT, French SS, Pfrender ME, Brodie ED 3rd, Brodie ED Jr. PLoS One. 2014 Jun 25;9(6):e100718.
Projection target-specific action of nicotine in the caudal nucleus of the - Projection target-specific action of nicotine in the caudal nucleus of the
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alpha2-containing GABAA receptors expressed in hippocampal region CA3 control - alpha2-containing GABAA receptors expressed in hippocampal region CA3 control
Heistek TS, Ruiperez-Alonso M, Timmerman AJ, Brussaard AB, Mansvelder HD. J Physiol. 2013 Feb 15;591(Pt 4):845-58.
Bicuculline- and neurosteroid-sensitive tonic chloride current in rat hypoglossal - Bicuculline- and neurosteroid-sensitive tonic chloride current in rat hypoglossal
Chesnoy-Marchais D. Eur J Neurosci. 2013 Feb;37(3):366-79.
Slowly inactivating component of Na+ current in peri-somatic region of - Slowly inactivating component of Na+ current in peri-somatic region of
Park YY, Johnston D, Gray R. J Neurophysiol. 2013 Mar;109(5):1378-90.
Gastrin-releasing peptide acts via postsynaptic BB2 receptors to modulate inward - Gastrin-releasing peptide acts via postsynaptic BB2 receptors to modulate inward
Hermes ML, Kolaj M, Coderre EM, Renaud LP. J Physiol. 2013 Apr 1;591(Pt 7):1823-39.
Serotonergic modulation of neuronal activity in rat midbrain periaqueductal gray. - Serotonergic modulation of neuronal activity in rat midbrain periaqueductal gray.
Jeong HJ, Lam K, Mitchell VA, Vaughan CW. J Neurophysiol. 2013 Jun;109(11):2712-9.
Presynaptic NMDA receptor mechanisms for enhancing spontaneous neurotransmitter - Presynaptic NMDA receptor mechanisms for enhancing spontaneous neurotransmitter
Kunz PA, Roberts AC, Philpot BD. J Neurosci. 2013 May 1;33(18):7762-9.
Huntington disease skeletal muscle is hyperexcitable owing to chloride and - Huntington disease skeletal muscle is hyperexcitable owing to chloride and
Waters CW, Varuzhanyan G, Talmadge RJ, Voss AA. Proc Natl Acad Sci U S A. 2013 May 28;110(22):9160-5. doi: