WNT7B

Gene Symbol WNT7B
Entrez Gene 7477
Alt Symbol -
Species Human
Gene Type protein-coding
Description wingless-type MMTV integration site family, member 7B
Other Description protein Wnt-7b
Swissprots Q96Q12 P56706 B8A596
Accessions CAI38649 EAW73394 P56706 AB062766 BAB68399 AF416743 AAN32640 AK123019 AK289526 BAF82215 BC034923 AAH34923 BM047487 CB853639 EU831473 ACE87160 EU831560 ACE86479 HQ447633 ADQ32118 XM_011530366 XP_011528668 NM_058238 NP_478679
Function Ligand for members of the frizzled family of seven transmembrane receptors. Probable developmental protein. May be a signaling molecule which affects the development of discrete regions of tissues. Is likely to signal over only few cell diameters (By similarity). {ECO:0000250}.
Subcellular Location Secreted, extracellular space, extracellular matrix.
Tissue Specificity Moderately expressed in fetal brain, weakly expressed in fetal lung and kidney, and faintly expressed in adult brain, lung and prostate.
Top Pathways Proteoglycans in cancer, Wnt signaling pathway, Signaling pathways regulating pluripotency of stem cells, Hippo signaling pathway, HTLV-I infection