| Gene Symbol | vps32 |
|---|---|
| Entrez Gene | 8619990 |
| Alt Symbol | DDBDRAFT_0167295, DDBDRAFT_0231531, DDB_0167295, DDB_0231531 |
| Species | Dictyostelium discoideum |
| Gene Type | protein-coding |
| Description | SNF7 family protein |
| Other Description | - |
| Swissprots | Q553K9 Q86H98 |
| Accessions | EAL69537 XM_638312 XP_643404 |
| Function | Probable core component of the endosomal sorting required for transport complex III (ESCRT-III) which is involved in multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins. {ECO:0000269|PubMed:15708561}. |
| Subcellular Location | Cytoplasmic vesicle membrane {ECO:0000269|PubMed:15708561}. Late endosome membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}. Note=Membrane-associated. Colocalizes to large vesicle-like structures with PDCD6IP/Alix. |
| Top Pathways | Endocytosis |