| Gene Symbol | OXCT2 |
|---|---|
| Entrez Gene | 64064 |
| Alt Symbol | FKSG25, SCOTT |
| Species | Human |
| Gene Type | protein-coding |
| Description | 3-oxoacid CoA transferase 2 |
| Other Description | 3-oxoacid CoA-transferase 2A|3-oxoacid-CoA transferase 2A|succinyl-CoA:3-ketoacid coenzyme A transferase 2, mitochondrial|succinyl-CoA:3-ketoacid-coenzyme A transferase 2, mitochondrial|testis-specific succinyl CoA:3-oxoacid CoA-transferase|testis-specific succinyl-CoA:3-oxoacid CoA-transferase |
| Swissprots | Q9H1I4 Q5QPK4 Q8NHR1 Q9BYC2 B2RBB4 |
| Accessions | CBH19406 Q9BYC2 AB050193 BAB40810 AK024440 BAB15730 AK093089 BAG52651 AK314586 BAG37161 AY013700 AAG33922 BC030015 BC072388 AAH72388 DQ893340 ABM84266 DQ896660 ABM87659 NM_022120 NP_071403 |
| Function | Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate (By similarity). {ECO:0000250}. |
| Subcellular Location | Mitochondrion {ECO:0000269|PubMed:11756565}. |
| Tissue Specificity | Testis specific. {ECO:0000269|PubMed:11756565}. |
| Top Pathways | Synthesis and degradation of ketone bodies, Valine, leucine and isoleucine degradation, Butanoate metabolism |