| Gene Symbol | APOA4 |
|---|---|
| Entrez Gene | 337 |
| Alt Symbol | - |
| Species | Human |
| Gene Type | protein-coding |
| Description | apolipoprotein A-IV |
| Other Description | apo-AIV|apoA-IV|apolipoprotein A4 |
| Swissprots | P06727 A8MSL6 Q14CW8 Q6Q787 |
| Accessions | AAA51745 AAA96731 AAQ91809 AAS68228 EAW67271 P06727 AL531739 BC074764 AAH74764 BC113594 AAI13595 BC113596 AAI13597 HQ258218 ADR82972 HQ258399 ADR83153 M10373 AAB59516 M13654 AAA51744 M14566 AAA51748 X13629 CAA31955 NM_000482 NP_000473 |
| Function | May have a role in chylomicrons and VLDL secretion and catabolism. Required for efficient activation of lipoprotein lipase by ApoC-II; potent activator of LCAT. Apoa-IV is a major component of HDL and chylomicrons. |
| Subcellular Location | Secreted. |
| Tissue Specificity | Synthesized primarily in the intestine and secreted in plasma. |
| Top Pathways | Fat digestion and absorption, Vitamin digestion and absorption |